ICMIC Seminar 01/05

January 2005 until December 2005

Listed below is the schedule for 3^rd year of our weekly P50 ICMIC Program meetings held on Wednesdays from 4 pm to 5 pm. The purpose of these meetings is to provide a forum for discussion and interaction, as well as to describe progress in the various projects of our JHU ICMIC Program. The first forty minutes of the meeting will focus on a scientific presentation, and the remaining fifteen to twenty minutes will be for discussion to include any issues for the attention of the ICMIC Oversight Committee.

Additionally, our monthly JHU ICMIC (Pizza) Seminar Series continues to be on the 2^nd Wednesday of every month at the usual time of 3:30 pm to 4:30 pm with pizza served from 3 pm to 3:30 pm. The monthly JHU ICMIC Seminars featuring an invited speaker are noted in blue.

Please note that the locations vary between Traylor 214, Ross G007, BRB G01, BRB G03, BRB G05, and BRB G07!

Date and Location

Title of the Presentation

Speaker

01/05/2005

Winter Break - Seminar will resume in February

01/12/2005

01/19/2005

01/26/2005

02/02/2005

02/09/2005

02/16/2005
Traylor 214

Efficient magnetic cell labeling with protamine sulphate complexed to ferumoxides for cellular MRI
AS Arbab, GT Yocum, H Kalish, EK Jordan, SA Anderson, AY Khakoo, EJ Read, JA Frank
Blood 2004;104(4):1217-1223

Barjor Gimi, Ph.D.
Postdoctoral Research Fellow
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

02/23/2005
BRB G01

Imaging Opportunities from the Myc Target Gene Network
Pilot Project
ICMIC

Chi V. Dang, M.D., Ph.D.
Professor
Johns Hopkins University School of Medicine
Dept. of Medicine - Hematology
Vice Dean for Research

03/02/2005
Traylor 214

Diffusion-weighted MRI Detects early Treatment Response after Antivascular Therapy of Prostate Tumors
Ongoing Project

Jens Vogel-Claussen, M.D.
Radiology Resident
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

03/08/2005
Tuesday
BRB G01

Spectroscopy In Vivo at 1.5T and 3T and on Biopsy at 8.5T

Carolyn Mountford, Ph.D.
Professor
University of Sydney
Chief Executive of Institute for Magnetic Resonance Research (IMRR)
Department of Magnetic Resonance in Medicine
Sydney, Australia

03/16/2005
BRB G03

Endothelin Receptor Imaging of Cancer
Piot Project
ICMIC

Jinsong Xia, Ph.D.
Postdoctoral Research Fellow
(Zsolt Szabo, M.D., Ph.D. – P.I.)
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

03/25/2005
Friday
BRB G03

Developing a New Class of CEST Reporter Genes
Pilot Project
ICMIC

Assaf Gilad, Ph.D.
Postdoctoral Research Fellow
(Peter C. M. van Zijl, Ph.D. - PI)
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

03/30/2005
BRB G07

Optical Imaging of Lysosomes In Vivo
Career Development Award
ICMIC

Kristine Glunde, Ph.D.
Instructor
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

04/06/2005
Traylor 214

Kinetics of Vascular Normalization by VEGFR2 Blockade Governs Brain Tumor Response to Radiation: Role of oxygenation, Angiopoietin-1, and Matrix Metalloproteinases.
F Winkler, SV Kozin, RT Tong, SS Chae, MF Booth, I Garkavtsev, L Xu, DJ Hicklin, D Fukumura, E di Tomaso, LL Munn, RK Jain
Cancer Cell 2004;6(6):553-563

Arvind P. Pathak, Ph.D.
Instructor
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

04/13/2005
BRB G05

Contrast-enhanced MRI of the Breast for Assessment of Response to Pre-operative Chemotherapy

Nola Hylton, Ph.D.
Professor in Residence, Radiology
University of California San Francisco (UCSF)
Comprehensive Cancer Center
San Francisco, CA, USA

04/20/2005

Seminar Cancelled
96^th Annual Meeting of the American Association for Cancer Research
Anaheim, CA, USA

04/27/2005
Traylor 214

Links Twist, A Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis.
J Yang, SA Mani, JL Donaher, S Ramaswamy, RA Itzykson, C Come, P Savagner, I Gitelman, A Richardson, RA Weinberg
Cell 2004;117(7):927-39

Farhad Vesuna, Ph.D.
Postdoctoral Research Fellow
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

05/04/2005

Seminar Cancelled

05/11/2005

Seminar Cancelled
13^th Scientific Meeting and Exhibition of the Society for Magnetic Resonance in Medicine, Miami, FL, USA

05/18/2005

Seminar Cancelled

05/25/2005
BRB G05

PSMA Based Imaging Agents
Pilot Project
ICMIC

Ronald Mease, Ph.D.
Associate Professor
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

06/01/2005
BRB G05

The Final Ending and New Beginnings - The Use of MR, MRS, CT, and PET in Cancer
Career Development Award
ICMIC

Michael Jacobs, Ph.D.
Assistant Professor
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

06/08/2005
BRB G05

New Magnetic Resonance Molecular Imaging Agents for Assessing Tumor Angiogenesis and Enzyme Biomarkers

Marty Pagel, Ph.D.
Assistant Professor
Case Western Reserve University
Dept. of Biomedical Engineering

06/15/2005
BRB G05

Engineering Molecular Probes for Imaging
Research Component
ICMIC

Venu Raman, Ph.D.
Assistant Professor
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

06/22/2005
Ross G007

Imaging the Role of HIF-1 in Breast Cancer Progression
Research Component
ICMIC

Gregg Semenza, M.D., Ph.D.
Professor
Johns Hopkins University School of Medicine
Institute of Genetic Medicine, Pediatrics, Oncology, Radiation Oncology and Molecular Radiation Sciences

06/29/2005
Traylor 214

HIF Activation by pH-dependent Nucleolar Sequestration of VHL
K Mekhail, L Gunaratnam, ME Bonicalzi, S Lee
Nat Cell Biol 2004;6(7):642-7

Paul Winnard, Ph.D.
Postdoctoral Research Fellow
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

07/06/2005

Seminar cancelled

07/13/2005
Ross G007

MR Perfusion Imaging of Brain Tumors: Promise and Potential Pitfalls

Kathleen Schmainda, Ph.D.
Associate Professor
Medical College of Wisconsin
Dept. of Radiology

07/20/2005
Ross G007

Molecular and Functional Imaging of the HER-2/neu Receptor
Research Component
ICMIC

Dmitri Artemov, Ph.D.
Associate Professor
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science and Dept. of Oncology

07/27/2005
Traylor 214

Dendrimer-based Imaging Contrast Agents

Vladimir Talanov, Ph.D.
Research Fellow
National Institute of Health NCI
Center for Cancer Research
Radiation Oncology Branch
Bethesda, MD

08/03/2005
BRB G07

Combined Anti-Angiogenic Therapy and siRNA Targeting of Choline Kinase
Research Component
ICMIC

Zaver Bhujwalla, Ph.D.
Professor
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science and Dept of Oncology
Director of JHU ICMIC Program

08/10/2005
Ross G007

Measuring the Iron Concentration in the Brain using MRI

Peter Hardy, Ph.D.
Assistant Professor
University of Toronto
Dept. of Biomedical Engineering
Toronto, Canada

08/17/2005
Traylor 214

Alterations in Galectin-3 Expression and Distribution Correlate with Breast Cancer Progression: Functional Analysis of Galectin-3 in Breast Epithelial-endothelial Interactions
MP Shekhar, P Nangia-Makker, L Tait, F Miller, A Raz
Am J Pathol 2004;165(6):1931-41

Noriko Mori, M.S., Ph.D.
Research Technician
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

08/24/2005
Traylor 214

Nanoparticle Targeting of Anticancer Drug Improves Therapeutic Response in Animal Model of Human Epithelial Cancer
JF Kukowska-Latallo, KA Candido, Z Cao, SS Nigavekar, IJ Majoros, TP Thomas, LP Balogh, MK Khan, JR Baker Jr
Cancer Res 2005;65(12):5317-24

Yoshinori Kato, Ph.D.
Postdoctoral Research Fellow
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

08/31/2005

Seminar Cancelled

09/07/2005

Seminar Cancelled
4^th Annual Meeting of the Society for Molecular Imaging
Cologne, Germany

09/14/2005
BRB G05

The Role of Nanoparticles in Functional and Molecular Imaging - A Paradigm for Personalized Medicine

Samira Guccione, Ph.D.
Acting Assistant Professor
Stanford University
Dept. of Radiology
Stanford, CA, USA

09/21/2005
Traylor 214

Quantitation of Cell Number by a Positron Emission Tomography Reporter Gene Strategy
H Su, A Forbes, SS Gambhir, J Braun
Mol Imaging Biol 2004;6(3):139-48

Catherine Foss, Ph.D.
Postdoctoral Research Fellow
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

09/28/2005
Traylor 214

Putting Tumours in Context
MJ Bissell, D Radisky
Nat Rev Cancer 2001;1(1):46-54

Ellen Ackerstaff, Ph.D.
Research Associate
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science and Dept. of Oncology

10/05/2005
Traylor 214

Cyclooxygenase (COX)-2 Inhibitor Celecoxib Abrogates TNF-induced NF-κB Activation through Inhibition of Activation of IκB α-kinase and Akt in Human Non-small Cell Lung Carcinoma: Correlation with Suppression of COX-2 Synthesis
S Shishodia, D Koul, BB Aggarwal
J Immunol 2004;173(3):2011-22

Ioannis Stassinopoulos, Ph.D.
Postdoctoral Research Fellow
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

10/12/2005
BRB G05

¹³C-NMR Evidence for an Association of Specific Cellular Metabolic Components with Early Molecular Events Leading to Apoptotic Cell Death Initiation

Claudia Zwingmann, Ph.D.
Professeur de recherche (invités)
Université de Montreal
Département de médicine
Centre de Recherche
Hôpital Saint-Luc, CHUM
Montreal, Quebec, Cananda

10/19/2005
BRB G03

Choline Kinase is a Novel Oncogene that Potentiates RhoA-induced Carcinogenesis
Cancer Res 2005;65(13):5647-53

Tariq Shah, Ph.D.
Research Trainee
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

10/26/2005

Seminar cancelled

11/03/2005
Ross G007
(Thursday)

Signal Amplification Probes in Molecular Imaging

Alexei A. Bogdanov, Jr., Ph.D.
Professor
Univ. of Massachusetts Medical School
Dept. of Radiology

11/07/2005
BRB G05
(Monday)

Role of PC Cycle Enzymes in Cell Proliferation and Tumor Progression

Franca Podo, Ph.D.
Director of Molecular and Cellular Imaging
Dept. of Cell Biology and Neurosciences
Instituto Superiore di Sanita
Rome, Italy

11/09/2005
BRB G05

A Novel HIF1-dependent Metabolic Switch and the Warburg Effect in Cancers

Chi V. Dang, M.D., Ph.D.
Professor
Johns Hopkins University School of Medicine
Dept. of Medicine - Hematology
Vice Dean for Research

11/16/2005

Seminar Cancelled

11/21/2005
BRB G03
(Monday)

Contrast Agents Applied to MRS and MRI

Ian J. Rowland, B.Sc.,Ph.D.
Danish Research Centre for Magnetic Resonance
Copenhagen University Hospital, Hvidovre
Dept. of MR
Hvidovre, Denmark

11/30/2005
BRB G07

Lysosomes in Cell Death Control and Cancer Invasion
Career Development Award
ICMIC

Kristine Glunde, Ph.D.
Assistant Professor
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science

12/07/2005

Seminar Cancelled

12/14/2005
BRB G07

Overview of the ICMIC Program

Zaver Bhujwalla, Ph.D.
Professor
Johns Hopkins University School of Medicine
Russell H. Morgan Dept. of Radiology & Radiological Science and Dept. of Oncology
Director of JHU ICMIC Program

12/21/2005

Winter Break - Seminar will resume in February 2006

12/28/2005

In Vivo Cellular Molecular Imaging Center (ICMIC)

Russell H. Morgan Department of Radiology and Radiological Science
Johns Hopkins University (JHU) School of Medicine
Baltimore, Maryland, USA

January 2005 until December 2005

In Vivo Cellular Molecular Imaging Center (ICMIC)

Russell H. Morgan Department of Radiology and Radiological Science Johns Hopkins University (JHU) School of Medicine Baltimore, Maryland, USA

January 2005 until December 2005

Russell H. Morgan Department of Radiology and Radiological Science
Johns Hopkins University (JHU) School of Medicine
Baltimore, Maryland, USA